The DNA in prokaryotic cells is significantly different from the DNA found in eukaryotic cells
“Prokaryote” means “before the nucleus”
The DNA is double-stranded
Prokaryotes possess a single, circular chromosomal DNA molecule
It is sometimes referred to as a nucleoid
They also usually have one or more plasmids
Plasmids are very small circular DNA molecules
They usually only contain a few genes
Plasmids are more accessible for proteins required for gene expression and therefore contain genes that are required often, quickly and/or in emergencies
The genes for antibiotic resistance are often found in plasmids
The DNA within prokaryotic cells is not associated with any proteins
Eukaryotic DNA associates with histone proteins
Image showing the arrangement of DNA within a prokaryotic cell