2018英特尔ISEF获奖作品摘要 行为与社会科学 Intel Finalist Abstract Behavioral and Social Sciences

获奖作品基本信息

年份	2018
学科	行为与社会科学 Behavioral and Social Sciences
国家/州	United State of America

获奖作品名称

The Effect of Metformin on Post Traumatic Brain Injury Learning and Learning Disabilities

获奖作品摘要

Traumatic brain injuries (TBIs) whether mild, moderate or severe, can have a direct and definite impact on a person’s everyday life. The initial treatment after TBI usually consists of interventions to train individuals to learn new knowledge and skills or new ways to access previously acquired knowledge and skills. Other treatments, like Deep Brain Stimulation which

works to stimulate the nerves around the lesion (injured) area, are highly invasive. Metformin, a drug??used for type 2 diabetes patients, has shown to promote neurogenesis in mice. ??This increase could potentially reverse the effects of a TBI by creating new nervous tissue to repair the lesion area.

This study used the??Drosophila melanogaster model, due to their fast-reproductive cycle and their similar nervous system to that of a human. ??Through the use of a T-maze the learning abilities of flies was tested as well as the effect of Metformin in different doses. ??Before testing flies were trained to associate a sucrose reward with an odor and no reward and another, then both were presented in the T-maze. ??It was found, using a One-way ANOVA test and a Tukey test, that 3.5 Add to dictionary of Metformin significantly increased learning in the flies given a TBI (p<.o5)

 

---

ISEF 简介

英特尔国际科学与工程大奖赛，简称 "ISEF"，由美国 Society for Science and the Public（科学和公共服务协会）主办，英特尔公司冠名赞助，是全球规模最大、等级最高的中学生的科研科创赛事。ISEF 的学术活动学科包括了所有数学、自然科学、工程的全部领域和部分社会科学。ISEF 素有全球青少年科学学术活动的“世界杯”之美誉，旨在鼓励学生团队协作，开拓创新，长期专一深入地研究自己感兴趣的课题。

>>> 实用链接汇总 <<<

英特尔 ISEF 学术活动详细介绍

英特尔 ISEF 全程指导方案

· 数学 · 物理 · 化学 · 生物 · 计算机 · 工程 ·

学科简介：行为与社会科学 Behavioral and Social Sciences

The science or study of the thought processes and behavior of humans and other animals in their interactions with the environment studied through observational and experimental methods.

Subcategories:

Clinical and Developmental Psychology (CLN): The study and treatment of emotional or behavioral disorders. Developmental psychology is concerned with the study of progressive behavioral changes in an individual from birth until death.

Cognitive Psychology (COG): The study of cognition, the mental processes that underlie behavior, including thinking, deciding, reasoning, and to some extent motivation and emotion.

Neuroscience (NEU): Studies of the neural basis of cognitive processes, including learning and memory, language and thought, perception, attention, and affect. It investigates the human brain, from the functional organization of large scale cerebral systems to microscopic neurochemical processes.

Physiological Psychology (PHY): The study of the biological and physiological basis of behavior. This field studies the neural mechanisms of perception and behavior through direct manipulation of the brain in controlled experiments.

Sociology and Social Psychology (SOC): The study of human social behavior, especially the study of the origins, organization, institutions, and development of human society. Sociology is concerned with all group activities-economic, social, political, and religious.

Other (OTH): Studies that cannot be assigned to one of the above subcategories. If the project involves multiple subcategories, the principal subcategory should be chosen instead of Other.